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title: Advancing TFF for Small Scale CGMP Production
description: Learn about a new single-use TFF system designed for process development and CGMP production of mRNA, gene therapies, and personalized medicine.
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# Advancing TFF for Small Scale CGMP Production

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## Presenter:

****![shanbaky-repligen-hs](https://bpi.bioprocessintl.com/hs-fs/hubfs/12-12-2023-Repligen-Smith-HS.png?width=136&height=197&name=12-12-2023-Repligen-Smith-HS.png)****

**Lucas Smith**

*Commercial Project Manager, TFF Systems,*

Repligen

 

Lucas Smith has six years of experience in the biotech and medical device industries and over 13 years in engineering systems. As an application engineer, he has consulted with Biotech companies worldwide on equipment design and selection with a focus on bioreactors, mixers, and TFF systems.  

He currently works in product management, aiding the development and delivery of innovative TFF systems by Repligen. Lucas has a bachelor's degree in biological engineering from Utah State University.

## About this event:

#### Date: May 9, 2024

#### Time: 11 am EDT | 8 am PDT | 5 pm CEST

#### Duration: 30 minutes

| The latest in TFF system innovation by Repligen is coming… Get an inside look into a new purpose-built single-use TFF system designed for process development and CGMP production of mRNA, gene therapies, and personalized medicine. While much of the equipment that is being leveraged for these applications today is repurposed from applications supporting significantly larger volume ranges, this system truly satisfies the demand for smaller scales. With unique features including complete end-to-end automation and real-time concentration measurement, this TFF system may be exactly what you need to produce your next blockbuster drug. Key Takeaways: - Introduction to new small-scale TFF system specifically designed for CGMP production of mRNA, gene therapies, and personalized medicine. - A review of built-in operational efficiency drivers such as real-time process analytics technology (PAT) and end-to-end automation beyond UF/DF steps. |
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