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Exploring On-Column mAb Aggregate Formation and Self-Generated On-Column pH Gradients
with Cation Exchange Resins

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Presenter:

William Rushton
William H. Rushton
Process Chromatography Support Scientist
Bio-Rad Laboratories
 
William Rushton is a Process Chromatography Support Scientist for customer support and method development at Bio-Rad Laboratories in North America. William has over 23 years of industry experience in Downstream Process Development. Prior to Bio-Rad, he worked at Centocor (wholly owned subsidiary of Johnson and Johnson) from 1997 to 2007 in the Process Development Group. While there he worked on ReoPro®, Remicade®, and developed the downstream purification processes for Simponi® and Stelara®. In 2007, he joined Charles River Laboratories as the manager of the Process Evaluation/Validation Group, performing viral clearance studies for Pharmaceutical and Biotech companies. Upon leaving Charles River in 2009, he supported the Biologics License Application (BLA) filing and post marketing activities for Xiaflex® at Auxilium Pharmaceuticals as a Senior Scientist in the Process Development Group. His work resulted in development of highly purified versions of the collagenases to improve analytical assay sensitivity as well as column validation work. He obtained a MS in Biomedical Sciences from Philadelphia College of Osteopathic Medicine and his BS in Biology from St. Joseph’s University.