Minimizing Lentiviral Vector Loss

During the Purification Process Using

an Innovative Nanofiber Adsorbent

Presenter:

Sujeong Yang, PhD
Viral Vector Lead, Senior Research Scientist,

Astrea Bioseparations

Sujeong Yang is a senior research scientist at Astrea Bioseparations, a pioneering company at the forefront of innovative bioseparations tools tailored for cell and gene therapy advancement and production. Sujeong plays an important role as an expert advisor in both upstream and downstream bioprocessing of viral vectors.

With over a decade of dedicated research experience, Sujeong has been a key contributor to the development of gene therapies centered around viral vectors. Her journey began in the field of neuroscience at the University of Cambridge, where she earned her doctoral degree in the subject. Following her studies, Sujeong continued her academic pursuits as a post-doctoral researcher and then as a fellow, all within University of Cambridge, UK.

About this event:

Date: October 26, 2023

Time: 11 am EDT | 8 am PDT |
5 pm CET

Duration: 15 minutes

The field of lentiviral vector (LVV)-based therapeutic applications, encompassing both ex vivo and in vivo gene therapy, is experiencing rapid growth. To meet the surging demand for LVV, it is imperative to address the bottlenecks associated with low LVV recovery and inadequate contamination removal. Traditional chromatography-based methods often suffer from poor step yield recovery, while non-chromatographic techniques may present challenges in terms of scalability and robustness.

In this webinar, learn about the challenges of LVV purification by introducing an innovative nanofiber adsorbent with high-flow and high-capacity properties.

Key takeaways:

Discover how Nereus LentiHERO^®, a novel spin column, streamlines the screening of process conditions, reducing the development time.
Explore the capabilities of the LentiHERO^® pre-packed FPLC capsule, which enhances process efficiency by offering both high LVV capacity and high LVV recovery rates.
Learn about the development of purification processes that effectively minimizes product loss in both adherent and suspension cultures, all while maintaining optimal processing speed.