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Moving Towards a Scalable AAV Vector
Production at High Volumetric Efficiency
Presenters:
Prasanna Srinivasan, PhDPrasanna Srinivasan, PhD is a research scientist in the Center for Biomedical Innovation at Massachusetts Institute of Technology, Cambridge. He earned his doctoral degree in materials science engineering from the University of Southampton, UK in 2008. Before joining MIT, he completed his postdoctoral training at La Jolla Institute of Immunology and UC Santa Barbara, working on the molecular mechanisms of calcium sensing ER proteins and engineered voltage sensors. He is a recipient of 2011 International Human Frontier Science Fellowship award and the 2015 Otis William Research Fellowship award. He has about 40 peer-reviewed publications in technical journals including Nature Communications, Nature Structural and Molecular Biology and Advanced Biology. He is also reviews manuscripts submitted to several technical journals and has given invited talks in several conferences and workshops. At MIT, he focuses on engineering recombinant viral vectors for in vivo gene delivery and AAV vector production via engineered manufacturable constructs, metabolic rewiring of cell line and development of improved bioreactor processes.
Graziella Piras, PhDGraziella Piras, PhD leads the strategic marketing activities for the life science division at 908 Devices. She has over 18 years of experience developing applications and solutions for upstream bioprocessing. Graziella previously held various R&D and marketing positions at Thermo Fisher Scientific, where she led projects to support the cell culture and cell therapy business. Graziella received her doctoral degree in biochemistry and molecular Biology from the University of Liège in Belgium. She did her postdoctoral studying the role of gene expression and epigenetic regulation on cancer and development at the National Cancer Institutes in Maryland.
