About this event:

Date: March 3, 2026

Time: 11 AM EST | 8 AM PST

5 PM CET

Duration: 30 minutes

As upstream intensification continues to drive monoclonal antibody (mAb) titers higher, downstream purification has emerged as the primary bottleneck for capacity, facility utilization, and cost of goods. Despite continuous chromatography being a promising solution, implementation on a commercial scale has proven challenging due to operational complexity, limited process control strategies, and the inertia of established batch platforms.

Downstream throughput and process economics can be notably improved by applying practical strategies.

This webinar will present experimental data and process models showing measurable cost reductions, including up to 80% lower buffer usage and 40% less resin volume.

Key Takeaways:

• Optimized Protein A capture.
• Strategic polishing resin selection.
• Flow-through versus bind-and-elute polishing.
• Inline dilution utilizing outsourced buffer preparation.